Novel Variant of Miller Fisher Syndrome
This case report describes a 43-year-old woman who presented to an acute medical team with a 3-day history of worsening diplopia.
View ArticleSubacute Imbalance in a Renal Transplant Patient
A woman in her 50s presented with a 1-month history of gait unsteadiness and imbalance, suspected to be due to neuropathy, but she then returned to the emergency department with 2 successive transient...
View ArticleImportance of Rare Subtypes in Peripheral Neuropathy
This review article describes rare localizations of peripheral neuropathy, including the appropriate diagnostic evaluation and available treatments.
View ArticlePrimary Leptomeningeal Lymphoma
A 69-year-old white man presented to the emergency department reporting 2 months of progressive bilateral lower extremity weakness, left facial weakness, and diplopia in the setting of a 20.4-kg weight...
View ArticleAmyloid Neuropathy Following Domino Liver Transplantation
This case report describes possible stabilization of liver transplant–acquired amyloid neuropathy with diflunisal.
View ArticlePrimary Leptomeningeal Lymphoma
A 69-year-old white man presented to the emergency department reporting 2 months of progressive bilateral lower extremity weakness, left facial weakness, and diplopia in the setting of a 20.4-kg weight...
View ArticlePhenotypic Variability of Childhood Charcot-Marie-Tooth Disease
This cross-sectional study assesses the variability of disease severity in a large cohort of children and adolescents with Charcot-Marie-Tooth disease.
View ArticlePrecision Medicine for Charcot-Marie-Tooth Disease
In this issue of JAMA Neurology, Cornett et al analyze clinical disability in 520 children and adolescents aged 3 to 20 years with Charcot-Marie-Tooth disease (CMT). Approximately half of the cohort...
View ArticleAssessment of Small Fiber Neuropathy
This case-control study compares the longitudinal rate and pattern of intraepidermal nerve fiber density change in idiopathic small fiber neuropathy (SFN), impaired glucose tolerance–associated SFN,...
View ArticleUnderstanding Small Fiber Neuropathy
Sensory predominant peripheral neuropathy is a common disorder, affecting as many as 10% of individuals older than 40 years. Many of these patients have small fiber neuropathy (SFN). Despite 3 decades...
View ArticlePharmacotherapy for Pain in Inherited Erythromelalgia
This double-blind, cross-over study of carbamazepine in 2 patients with inherited erythromelalgia aims to determine whether pain can be attenuated via pharmacotherapy guided by genomic analysis and...
View ArticleUnderstanding Atomic Interactions to Achieve Well-being
Voltage-gated sodium channels are among the most active and ubiquitous molecular machines found in animals. Residing in the cell membranes of excitable and other cells, they derive energy for their...
View ArticleChemotherapy-Induced Peripheral Neuropathy and the Risk of Falling
This study explores the association between the symptoms of chemotherapy-induced peripheral neuropathy and the risk of falls for patients receiving neurotoxic chemotherapy.
View ArticleContactin-Associated Protein-like 2 Antibodies
In 2007, the detection of IgG antibodies against the N-methyl-d-aspartate receptor in young women with encephalopathy opened a new field in neurology: the study of encephalitides with antibodies...
View ArticleChemotherapy-Induced Peripheral Neuropathy and the Risk of Falling
This study explores the association between the symptoms of chemotherapy-induced peripheral neuropathy and the risk of falls for patients receiving neurotoxic chemotherapy.
View ArticleRapidly Progressive Quadriplegia and Encephalopathy
This case report describes a patient with a rapidly progressive diffuse sensory motor axonopathy on serial electrodiagnostic testing and generalized slowing to bilateral periodic lateralized...
View ArticleAssociation of Albumin Levels With Guillain-Barré Syndrome Outcomes
This cohort study assesses the association between serum albumin levels and the clinical course and outcome of Guillain-Barré syndrome in patients treated with intravenous immunoglobulin.
View ArticleDiagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis
This study assesses the ability of neurofilament light chain to serve as a diagnostic biomarker in amyotrophic lateral sclerosis and the prognostic value of cerebrospinal fluid neurofilament light...
View ArticleLong-term Opioid Therapy Among Patients With Polyneuropathy
This population-based cohort study quantifies the prevalence of long-term opioid use among patients with polyneuropathy and assesses the association of long-term opioid use with functional status,...
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